Reshaping the energy landscape transforms the mechanism and binding kinetics of DNA threading intercalation
Andrew G Clark, M Nabuan Naufer, Fredrik Westerlund, Per Lincoln, Ioulia Rouzina, Thayaparan Paramanathan*, and
Mark C Williams
Biochemistry 57 (5): 614-619 (2018)
Mechanisms of small molecule-DNA interactions probed by single-molecule force spectroscopy
Ali Almaquashi, Thayaparan Paramanathan, Ioulia Rouzina, and Mark C. Williams.
Nucleic Acids Research 44 (9): 3971-3988 (2016)
A general mechanism for competitor-induced dissociation of molecular complexes
Thayaparan Paramanathan, Daniel Reeves, Larry Friedman, Jane Kondev and Jeff Gelles
Nature Communications 5: 5207 (2014)
Strong DNA deformation required for extremely slow DNA threading interaction by a binuclear ruthenium complex
Ali Almaquashi, Thayaparan Paramanathan, Per Lincoln, Ioulia Rouzina, Fredrik Westerlund and Mark C. Williams.
Nucleic Acids Research 42 (18): 11634-11641 (2014)
Force spectroscopy reveals the DNA structural dynamics that govern the slow binding of Actinomycin D
Thayaparan Paramanathan, Ioana D. Vladescu , Micah J. McCauley, Ioulia Rouzina and Mark C. Williams.
Nucleic Acids Research 40 (11): 4925-4932 (2012)
Studying Nucleic Acid-Drug Interactions at the Single Molecule Level Using Optical Tweezers
Thayaparan Paramanathan, Micah J. McCauley and Mark C. Williams
Book Chapter in Methods for Studying DNA/Drug Interactions—CRC Press (2011)
DNA Stretching as a Probe for Nucleic Acid Interactions: Reply to Comments on 'Biophysical characterization of DNA binding from single molecule force measurements
Micah J. McCauley, Kathy R. Chaurasiya, Thayaparan Paramanathan, Ioulia Rouzina and Mark C. Williams
Physics of Life Reviews 7: 358-361 (2010)
Biophysical Characterization of DNA Binding from Single Molecule Force Measurements
Kathy Chaurasiya, Thayaparan Paramanathan, Micah J. McCauley and Mark C. Williams
Physics of Life Reviews 7: 299-341 (2010)
Mechanically Manipulating the DNA Threading Intercalation Rate
Thayaparan Paramanathan, Fredrik Westerlund, Micah J. McCauley, Ioulia Rouzina, Per Lincoln and Mark C. Williams.
Journal of the American Chemical Society 130: 3752-3753 (2008)
Underlined Authors are Undergraduate Researchers
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