Quantifying Anticancer Drug Doxorubicin Binding to DNA using Optical Tweezers

Zachary Ells, Brian Dolle, Thayaparan Paramanathan

Biophysical Journal 116 (3), 506a (2019) 

Investigating How Chirality of a Threading Binuclear Ruthenium Complex Affects the DNA Threading Intercalation using Optical Tweezers

Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina,

Mark C Williams, Thayaparan Paramanathan

Biophysical Journal 116 (3), 140a (2019)  

Role of Threading Moiety Size and Chirality in Determining the DNA Binding Characteristics of Threading Intercalators

Thayaparan Paramanathan, Andrew Clark, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley,

Ioulia Rouzina, Mark C Williams 

Biophysical Journal 112 (3), 517a (2017) 

Significance of Steric Bulk in DNA Threading Intercalation Revealed through Force-Dependent Kinetics

Andrew G Clark, Thayaparan Paramanathan, Fredrik Westerlund, Per Lincoln, Micah McCauley, Ioulia Rouzina,

Mark Williams

Biophysical Journal 110 (3), 241a (2016) 

Role of the Moiety Chirality in Determining the DNA Binding Characteristics of Threading Intercalators

Thayaparan Paramanathan, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah McCauley, Ioulia Rouzina,

Mark C Williams

Biophysical Journal 110 (3), 561a (2016)

Constructing Dual Beam Optical Tweezers for Undergraduate Biophysics Research

Brian Daudelin, Devon West-Coates, Jon Del'Etoile, Eric Grotzke, Thayaparan Paramanathan

Bulletin of the American Physical Society (2016)

Quantifying the DNA binding characteristics of ruthenium based threading intercalator Λ Λ -P with optical tweezers

Nicholas Bryden, Micah McCauley, Fredrik Westerlund, Per Lincoln, Ioulia Rouzina, Mark Williams,

Thayaparan Paramanathan

Bulletin of the American Physical Society (2016)

Threading Moieties Play a Significant Role in Determining the DNA Binding Properties of Binuclear Ruthenium Complexes

Thayaparan Paramanathan, Andrew Clark, Fredrick Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina,

Mark C Williams

Bulletin of the American Physical Society (2015)

The Role of the Threading Moiety in DNA Threading Intercalation by Ruthenium Dimer Complexes

Andrew Clark, Thayaparan Paramanathan, Fredrick Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina,

Mark C Williams

Biophysical Journal 108 (2), 398a (2015)

Competitor Effect on Molecular Complex Dissociation in the Absence of Ternary Complex Formation

Thayaparan Paramanathan, Daniel Reeves, Larry Friedman, Jane Kondev and Jeff Gelles

Biophysical Journal 108 (2), 164a (2015)

Underlined Authors are Undergraduate Researchers

Publications in Abstract form -  Prior to BSU