Quantifying Anticancer Drug Doxorubicin Binding to DNA using Optical Tweezers

Zachary Ells, Brian Dolle, Thayaparan Paramanathan

63rd Annual Meeting of the Biophysical Society @ Baltimore, MD (March 2-6, 2019) 

Investigating How Chirality of a Threading Binuclear Ruthenium Complex Affects the DNA Threading Intercalation

using Optical Tweezers

Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina,

Mark C Williams, Thayaparan Paramanathan

63rd Annual Meeting of the Biophysical Society @ Baltimore, MD (March 2-6, 2019)  

Investigating How Chirality of a Threading Binuclear Ruthenium Complex Affects the DNA Threading Intercalation

using Optical Tweezers

Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina,

Mark C Williams, Thayaparan Paramanathan

62nd Annual Meeting of the Biophysical Society @ San Francisco, CA (Feb 17-21, 2018)  

Role of Threading Moiety Size and Chirality in Determining the DNA Binding Characteristics of Threading Intercalators

Thayaparan Paramanathan, Andrew Clark, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley,

Ioulia Rouzina, Mark C Williams 

61st Annual Meeting of the Biophysical Society @ New Orleans, LA (Feb 11-15, 2017)

Role of the Moiety Chirality in Determining the DNA Binding Characteristics of Threading Intercalators

Thayaparan Paramanathan, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah McCauley, Ioulia Rouzina,

Mark C Williams

60th Annual Meeting of the Biophysical Society @ Los Angeles, CA (Feb 27 - Mar 2, 2016)

Constructing Dual Beam Optical Tweezers for Undergraduate Biophysics Research

Brian Daudelin, Devon West-Coates, Jon Del'Etoile, Eric Grotzke, Thayaparan Paramanathan

American Physical Society March Meeting @ Baltimore, MD (March 14-18, 2016)

Quantifying the DNA binding characteristics of ruthenium based threading intercalator Λ Λ -P with optical tweezers

Nicholas Bryden, Micah McCauley, Fredrik Westerlund, Per Lincoln, Ioulia Rouzina, Mark Williams,

Thayaparan Paramanathan

American Physical Society March Meeting @ Baltimore, MD (March 14-18, 2016)

Threading Moieties Play a Significant Role in Determining the DNA Binding Properties of Binuclear Ruthenium Complexes

Thayaparan Paramanathan, Andrew Clark, Fredrick Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina,

Mark C Williams

American Physical Society March Meeting @ San Antonio, TX (March 2-6, 2015)

Competitor Effect on Molecular Complex Dissociation in the Absence of Ternary Complex Formation

Thayaparan Paramanathan, Daniel Reeves, Larry Friedman, Jane Kondev and Jeff Gelles

60th Annual Meeting of the Biophysical Society @ Baltimore, MD (Feb 7-11, 2015)

Bold font indicates the Lead Presenters and Underlined Authors are Undergraduate Researchers