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CURRICULUM VITAE

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Dr. Jeff Bowen

Jeffery A. Bowen, Ph.D.

Professor and Chair of Biology
Department of Biological Sciences
Bridgewater State College
Bridgewater, MA 02325
Tel: (508) 531-2098 Fax: (508) 531-1785
E-mail: jabowen@bridgew.edu

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Education

Experience

Grants

Honors & Societies

Publications

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Education:

 

Participant.   Marine Biological Laboratory.
Analytical and Quantitative Light Microscopy Short Course, 2007 

University of Kansas Medical Center

Post-Doctoral Fellowship, 1999
University of Kansas Medical Center
Center for Reproductive Sciences
NIH Fellowship (NRSA)
Lalor Fellowship
Specialization:Reproductive Physiology & Reproductive Immunology
Advisor: Dr. Joan Hunt

College of Veterinary Medicine

Ph.D. Veterinary Anatomy, 1996
Texas A&M University
Specialization:
Reproductive Physiology and Cellular Biology
Dissertation Title:The Development and Characterization of an In Vitro Model System of Porcine Uterine Epithelium
Advisors: Drs. Robert Burghardt & Fuller Bazer.

Cal Poly Pomona

M.S. Agriculture, 1990.
California State Polytechnic University, Pomona,
Specialization:
Animal Science and Reproductive Physiology
Thesis Title: Diluent Osmolality and Porcine Spermatozoa.
Advisor: Dr. Edward Fonda.

Cal Poly Pomona

B.S. Animal Science, 1987.
California State Polytechnic University, Pomona
Specialization: Pre-Vet Option.

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Professional Experience:

Teaching Experience:

Courses

            Principles of Biology (BIOL-100) Lecture and Lab: Gen. Ed. Course

            The Biology of Human Sexuality* (BIOL-128): Gen. Ed Course

            General Biology I (BIOL-121) Lecture and Lab: Bio-Major Core Course

            Histology (BIOL-371) Lecture and Lab: Biology Elective

            Immunology (BIOL-375): Lecture-based course: Biology Elective

            General Endocrinology (BIOL-376) Lecture-based course: scheduled to teach

            Embryology (BIOL-430): Lecture and Lab: Biology Elective

            Electron Microscopy (BIOL-434): Lecture and Lab: Biology Elective

            Reproductive Physiology* (BIOL-436): Lecture and Lab: Biology Elective

            Special Topics (BIOL-490): 1-3 credit trial courses meant as a one-time offering

                        Light Microscopy*: Bioethics*: BSC CityLab Techniques:  Biology Electives

            Research (BIOL-497): Lab-based and small group discussions: Biology Electives

            Advanced Topics in Cell/Molecular Biology (BIOE-513)

                        Various 3-4 credit courses for the Masters of Arts in Biology Program

            Advanced Topics in Biomedical/Physiology Biology (BIOE-514)

                        Various 3-4 credit courses for the Masters of Arts in Biology Program

            *New courses to the Department

2009 – Current

            Professor of Biology in the Department of Biological Sciences, Bridgewater State College Bridgewater, MA 02325.  

2008 – 2009

            Chair,Department of Biological Sciences, Bridgewater State College Bridgewater, MA 02325.

2005 – 2009

            Associate Professor in the Department of Biological Sciences, Bridgewater State College Bridgewater, MA 02325.  

1999 (Sept.)- 2005

Assistant Professor in the Department of Biological Sciences, Bridgewater State College, Bridgewater, MA. Responsibilities include teaching introductory Biology courses and laboratories, upper level courses in Microscopy and Embryology/Developmental Biology. Develop courses specific to the goals of the upper level courses appropriate for the department’s biomedical/molecular concentration. Additional contributions to the overall development of the department will be made, including a strong commitment to teaching and research in an undergraduate setting, advising undergraduate students, participating in equipment procurement and supervising original undergraduate research.

1998 (June); 1999 (June)

Teaching Assistant for Frontiers in Reproductive Biology, Marine Biological Laboratories, Woods Hole, MA. Responsible for preparing laboratory experiments, conducting demonstrations and preparing and designing the laboratory manual. The Short Course is designed to give senior graduate students, post-docs, MDs wanting to get involved in research and assistant professors a brief but intense course in the techniques used in reproductive biology. Our modules covered embryo transfer, stem cell technology, comparative reproductive anatomy and reproductive immunology.

1991-1996

Graduate Research Assistant: Supervised and coordinated scientific projects for senior project students, and Veterinary student summer research programs. Instructed fellow graduate students and technicians on scientific techniques and methodology.

1996

Mentor: Summer Bridging Program for incoming freshmen and high school seniors. Student Ismael Valdes. A program designed to expose minority students to science and campus life. The program allowed them to live on campus, work in a laboratory and present their scientific work in a seminar atmosphere.

1994

Mentor: Senior project student Cynthia Rowe. Monitored her growth as a scientist by demonstrating techniques, supervised her experimental design and approach and aided her analysis of the data. (She’s now attending Tufts Veterinary School.)

1992-1993

Graduate Teaching Assistant: Undergraduate Histology; Prepared and conducted lab assignments and lectured on endocrinology and reproductive biology; Dr. Michael Tatum and Dr. Evelyn Tiffany-Castiglioni, Advisors.

1988-1990

Graduate Technician: Responsibilities included the management of experiments of senior project students, lecturing in Reproductive Physiology and Endocrinology courses and conducting various classroom laboratory experiments.

Research Experience:

1997 (July) - 1999 (June)

Lalor Foundation Fellow: Peered reviewed grant application designed to examine the interaction between TNF" and placental adhesion molecules. Renewed for a second year.

1996 (Nov) - 1997 (Nov)

NRSA Training Fellow: First trainee in the Center for Reproductive Sciences at KUMC. Examined the interaction between TNF" and its receptors during implantation and early pregnancy and their effects on cell adhesion molecules including integrins, CAM-family, and selectins.

1995 (Dec) - 1996 (Oct)

Assistant Research Scientist: Direct research efforts in the laboratory. Specifically, the study of the interaction between uterine epithelium and conceptus and the maintenance of the prereceptive and receptive stages of the uterus using probes to a variety of molecules including; Muc-1, integrins and sugar moieties. Also continued the development and utilization of the uterine in vitro model system.

1991-1995

Graduate Research Assistant: Conducted scientific research aimed at understanding the underlying cellular response of the uterus to embryo implantation. Supervised and coordinated scientific projects for senior project students, and Veterinary student summer research programs.

1988-1990

Graduate Technician: Operated Cal Poly University's Semen Lab, responsibilities included the management of experiments (including senior projects), monitoring cryopreserved semen, ova and embryos, and conducting various classroom laboratory experiments.

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Grant Support:

 

National Institutes of Health-AREA R-15:
The role ofαB-crystallin in chemoresistance of retinoblastoma
Two year,$187,582. 2008-2009
MeridethKrevosky, Ph.D., PI: Jeffery Bowen, Ph.D., Co-PI

HP Technology for Teaching Grant Initiative
TabletPCApproaches to Enhanced Learning in Undergraduate Science Instruction.2008
Investigators: R.G. Amey, F. Gorga, and J.A. Bowen
Grant was not funded; however, we received permission to pilot the programthrough IT during the Spring

                                                            2009semester.

                                               
LI-COR Biosciences Undergraduate Training Award:                                              

            DNA Sequencer

            Awarded: LICOR DNA Sequencer in May 2005

            Principal Investigators:  Drs Frank Gorga and Hardy Moore

                        Co-PIs: Drs. Bowen, Carson, Krevosky, LaBonte, and Mancini

 

NSF-CCLI: Course Curriculum Development:

Cognitive Apprenticeship in the Core Laboratories of Majors’ Biology:  Dedicated Equipment Supports the Learning Environment.                 

3 years, $300,000 – submitted May, 2005

Patricia E. Mancini, Ph.D., PI: Jeffery Bowen and Merideth Krevosky, Co-PIs.

(Resubmission of the unfounded CCLI grant)

 

National Institutes of Health – Science Education Partnership Award.

            Biotech for Students and Teachers: Phase II:

            2 years, $230,000.  Oct. 1 2005 -2007

            Michael Carson, Ph.D., PI; Jeffery Bowen, Ph.D. Co-PI.

 

National Institutes of Health – Science Education Partnership Award.

            BSC CityLab.

            4 years, $800,000.  Sept 1, 2000 -2004;

            John Jahoda, Ph.D. Original PI;

            Jeffery A. Bowen, Ph.D., and Michael Carson, Ph.D. assumed responsibilities in 2002.

 

Rewarding Youth Acheivement

            “DNA Fingerprinting Camp: Lab Larceny” for Brockton Public Schools.

            $8,435 in 2001

            $8,928.50 in 2002

            Dr. Jeffery Bowen, PI; Drs. Carson, Gorga, and Mancini Co-PIs.

 

Faculty and Librarian Research Grant  

The Synthesis Of Diethylester Glutathione Conjugates As Potential Cell Membrane Permeable “Arrows” Against Anti-Cancer Target Enzymes

            $4,000; May, 2000 – Sept, 2000.

Received one of the first grants from this new initiative from the Center for the Advancement of Research and Teaching.

            Joint project with the Department of Chemistry

            Ed Brush, Ph.D. & Jeff Bowen, Ph.D. PIs

 

Lalor Foundation Fellowship:

            TNFα Regulation of Cell Adhesion Molecules in the Placenta

            $25,000; 1 July, 1998 - 30 June, 1999 ;

            Jeffery Bowen, Ph.D. PI

                        J.S. Hunt, Mentor. Competitive Renewal

 

Lalor Foundation Fellowship:

            TNFα Regulation of Cell Adhesion Molecules in the Placenta

            $22,500; 1 July, 1997 - 30 June, 1998

            Jeffery Bowen, Ph.D. PI

                        J.S. Hunt, Mentor.

 

NRSA - NIH Training Grant (Institutional):

            Reproductive Biology: Early Pregnancy and Development

            $225,000; 1 May, 1996 - 30 April, 2001

            M.J. Soares, P.I.

            J.S. Hunt, Mentor. ($19,000/year).

 

Unsuccessful Grants

 

National Science Foundation — Math and Science Partnership Award.  

            Improved Science Education for the Transitional Middle School

            5 years, $12.5 million. Submitted 2003.

Carl Franzblau, Ph.D. PI (BUSM), Jeffery Bowen, Ph.D. Co-PI (lead at BSC); Carla Romney, Ph.D. Co-PI.  

 

National Science Foundation — CCLI-Education Material Development.

The Marriage of Science and Education: Engaging the Science-Phobic Non-major with Inquiry-based Biology Laboratory Modules;

            3 years, $75,000.  Submitted 2003

            Jeffery A. Bowen, Ph.D., PI; Patricia Mancini, Co-PI.

             

Merck/AAAS Undergraduate Science Research Program

Project Directors: Dr. Edward Brush, Department of Chemical Sciences, and Dr. Jeffery Bowen, Department of Biological Sciences.  

            Submitted November 1999; re-submitted November 2000.

 

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Program Development:

            BSC Mentoring Program for Student

This program, tentatively called Navigator, is a program I have initiated with Theresa Coogan (Counseling Education) and the office of Student Affairs.  The goals of this program are to: 1. unite the various mentor-like programs on campus (such as Project Compass and GLBTA), and 2. provide our students with a safe-place to go when they are faced with personal or school related problems.  The program is currently being developed but is hoped to be a campus-wide program to assist our students in finding the help they need. 

            Friday Informal Seminar Hour (FISH)

                        Together with Dr. Merideth Krevosky and based on a program brought to BSC by Dr. Kevin Curry after his sabbatical at Dalhousie University, we created this informal seminar series with several goals to promote student development and interaction, which includes opportunities for students to discuss and present their data, discuss post-graduation opportunities, and to hear presentations from guest lecturers in science as well as other disciplines.

             Image Analysis Laboratory

                        Established and currently serve as Director of the IAL.  Lab includes two Zeiss 9c Transmission Electron Microscopes and associated EM equipment.  Lab has expanded to include: a Zeiss photomicroscope with fluorescent and DIC capabilities; an Olympus BX-51 microscope with fluorescent, DIC, and digital imaging capabilities; and a Kodak Gel Imaging system.

             Faculty Advisory Network

Established a mentoring-like network for new and current faculty.  The program is designed as a faculty to faculty peer support network to help faculty navigate through the complexities of the institution.

             BSC CityLab (CASE)

                        Served as Co-Director (2001-2005) of this K-12 Biotechnology Outreach Progam.  Designed inquiry-based and hands-on experiences for area youth.  Instrumental role in two successful NIH-Science Education Partnership Awards and the institutionalization of the program into the college community through the development of the Center for the Advancement of Science Exploration (CASE).

             BSC Mentor Program

Currently developing and piloting a program to be initiated campus wide for a defined mentoring program that will serve as a safe and confidential resource for students.  The BSC Mentor will provide students with a willing listener to help them deal with problems ranging from personal issues to career options and graduate school.

             Sustainability Center

A faculty-driven initiative to establish a center for sustainability for Southeastern Massachusetts at Bridgewater State College and to spawn and nurture programs that will help make this region more vibrant economically, more restorative environmentally, and more sensitive to the social needs of all its citizens.

 

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Honors, Societies and Ad hoc Reviewing:

Honors

Presidential Award for Distinguished Teaching, 2006  (Inaugural Award)

ATP Undergraduate Research Faculty Mentor Award, 2005

Honors Outstanding Professor Award, 2004   (Inaugural Award)

Beta Beta Beta, National Biology Honors Society, Bridgewater State College, 2004

Teaching Assistantship, Frontiers in Reproduction, Marine Biological Laboratory, Woods Hole, MA 1998, 1999

            Lalor Foundation Fellowship, KUMC 1997, 1998.

                                    National Institutes of Health Training Fellowship (Institutional NRSA), KUMC 1996.

                                    Sigma Xi, Scientific Research Society, California State Polytechnic University, Pomona 1989.

            Gamma Sigma Delta, Honor Society of Agriculture, Cal Poly, Pomona 1989.

 

            Societies

American Society of Animal Scientists (1987-1992)

Society for the Study of Reproduction (1991 - current)

                        Inducted to full membership (2000)               

                        Committee for Minority Affairs (2000 - 2001)

                        State Representative (2005-current)

National Association of Biology Teachers (2001 - current)

BioLab (1997 - current)

Biophotonics (2001 - current)

Biotechniques (1998 - current)

 

            Ad Hoc Reviewer

            Biology of Reproduction

            Immunology Today

            Journal of Reproductive Immunology           

            Domestic Animal Endocrinology

 

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Publications:

Review Articles:

1. Bowen J.A., R.C. Burghardt. 2000. The molecular and cellular mechanisms of implantation in the domestic animal. Seminars in Cell and Developmental Biology. (In Press).

2. Bowen J.A., J.S. Hunt. 2000. Adhesion molecules and placental development. Proceedings of the Society for Experimental Biology and Medicine. (In Press)

3. Hunt J.S., T.A. Phillips, C.A. Rasmussen, J.A. Bowen, H. Bluethmann. 1999. Apoptosis-inducing members of the tumor necrosis factor supergene family: Potential functions in placentae. Trophoblast Research 13:243-257.

4. Hunt J.S. T. Phillips, J Pace, S. Banerjee, J.A. Bowen. 1999. The TNF superfamily and placental development. Trophoblast Research 12:1-11.

5. Burghardt R.C., J.A. Bowen, G.R. Newton and F.W. Bazer. 1997. Extracellular matrix and the implantation cascade in pigs. In: Control of Pig Reproduction V. Journal of Reproduction and Fertility. Suppl 52:151-164.

Book Chapter:

R.C. Burghardt, J.A. Bowen, F.W. Bazer. 1998. Chapter 8: Endocrine control of trophoblast-uterine interactions and the peri-implantation process. In: Bazer, F.W. (Ed.). Contemporary Endocrinology Series: Endocrinology of Pregnancy. Humana Press Inc. Totowa, NJ.

Manuscripts:

1. Bowen J.A. J.L. Pace, J.S. Hunt. Expression of integrin subunits "v and $3 in mouse trophoblast cells Is regulated by tumor necrosis factor-" through tumor necrosis factor receptor-2. Biology of Reproduction. (Submitted)

2. Kaufman K., J.A. Bowen, A.F. Tsai, J.A. Bluestone, J.S. Hunt, and C. Ober. 1999. The CTLA-4 gene is expressed in placental fibroblasts. Molecular Human Reproduction. 5: 84-87.

3. Bowen J.A., J.S. Hunt. 1999. Expression of cell adhesion molecules in murine placentas and a trophoblast cell line. Biology of Reproduction. 60:428-434.

4. Newton G.R., D.W. Weise, J.A. Bowen, S. Woldesenbet, RC Burghardt. 1998. Regulation of protein and prostaglandin secretion in polarized primary cultures of caprine uterine epithelial cells. In Vitro Cell & Developmental Biology. 34:578-584.

5. Day*, W.E., J.A. Bowen*, R. Barhoumi, F.W. Bazer and R.C. Burghardt. 1998. Endometrial connexin expression during non-invasive implantation: Analysis in equine and porcine model systems. Anatomical Record. 251:277-285. *Denotes equal contribution.

6. Bowen, J.A., F.W. Bazer and R.C. Burghardt. 1997. Spatial and temporal analyses of integrin and Muc-1 expression in porcine uterine epithelium and trophectoderm in vitro. Biology of Reproduction. 56:409-415.

7. Bowen, J.A., F.W. Bazer and R.C. Burghardt. 1996. Spatial and temporal analyses of integrin and Muc-1 expression in porcine uterine epithelium and trophectoderm in vivo. Biology of Reproduction. 55:1098-1106.

8. Bowen, J.A., G.R. Newton, D.W. Weise, F.W. Bazer and R.C. Burghardt. 1996. Structural and functional studies of polarized porcine uterine epithelium. Biology of Reproduction. 55:613-619.

9. Burghardt, R.C., R. Barhoumi, T.C. Sewall and J.A. Bowen. 1995. Cyclic AMP induces rapid increases in gap junction permeability and changes in the cellular distribution of connexin43. Journal of Membrane Biology. 148:243-253.

10. Barhoumi, R., R.H. Bailey, R.W. Hutchinson, J.A. Bowen and R.C. Burghardt. 1995. Enhancement of melphalan toxicity by altering cell-cell communication and plasma membrane fluidity with octanol in ovarian adenocarcinoma cell lines. Fundamental & Applied Toxicology. 25:70-79.

11. Varner, D.D., J.A. Bowen and L. Johnson. 1993. Effect of heparin on capacitation/acrosome reaction of equine sperm. Archives of Andrology. 31:199-207.

12. Barhoumi, R., J.A. Bowen, L.S. Stein, J. Echols and R.C. Burghardt. 1993. Concurrent analysis of intracellular glutathione content and gap junctional intercellular communication. Cytometry. 14:747-756.

13. Varner, D.D., J.A. Bowen and L. Johnson. 1992. Capacitation and acrosome reaction of equine spermatozoa by heparin. Molecular Andrology. 4:81-100.

14. Garcia, M.A., J.A. Bowen, E.S. Fonda and M.J. Burrill. 1989. Acrosin extraction and quantitation in porcine spermatozoa. Western Section of the American Society of Animal Scientists. 41: 393-396.

15. Bowen, J.A., E.S. Fonda, and D.L. Kooyman. 1988. Ultrastructural study of goat spermatozoa frozen at different diluent osmolalities. Western Section of the American Society of Animal Scientists. 39:312-315.

16. Bowen, J.A., E.S. Fonda, and D.L. Kooyman. 1988. A Morphological study of caprine spermatozoa frozen at different diluent osmolalities. Western Section of the American Society of Animal Scientists. 39:243-248.

Laboratory Manuals:

1. J.A. Bowen, and J.S. Hunt. 1999. Reproductive Immunology; Module 3 In: Frontiers in Reproduction: Cellular and Molecular Applications. J.S. Hunt, K. Mayo, G. Schatten (Eds). Marine Biological Laboratories, Woods Hole, MA.

2. J.A. Bowen, and J.S. Hunt. 1998. Reproductive Immunology; Module 3 In: Frontiers in Reproduction: Cellular and Molecular Applications. J.S. Hunt, K. Mayo, G. Schatten (Eds). Marine Biological Laboratories, Woods Hole, MA.

Abstracts:

1. Hunt J.S. T. Phillips, J Pace, S. Banerjee, J.A. Bowen. 1998. The TNF superfamily and placental development. International Placental Group, Oct. 21-26. Tokyo, Japan.

2. Hunt, J.S., C.A. Rasmussen, and J.A. Bowen. 1997. The tumor necrosis factor gene family and pregnancy. Fetal & Neonatal Physiology Symposium. June 25-29, 1997. Cambridge, UK.

3. Bowen, J.A., C.A. Rasmussen, and J.S. Hunt. 1997. Integrin expression by murine trophoblastic cell lines. Journal of Reproductive Immunology. 34:60 (abstr 46).

4. Bowen, J.A., C.A. Rasmussen, S. Banerjee, J.S. Hunt. 1997. Expression of integrin subunits by a murine trophoblast cell line. Biology of Reproduction. 56 (Suppl 1):190 (abstr 430).

5. Glasser, S.R., G. Wang, F.W. Bazer, J.A. Bowen, R.C. Burghardt. 1996. Polarized uterine epithelial cells: Comparative in vitro models of non-invasive vs. invasive implantation. Third World Conference on Early Pregnancy. Oct. 3-6, 1996. Atlantic City, NJ.

6. Burghardt, R.C., J.A. Bowen, W.E. Day, R. Barhoumi, F.W. Bazer, S.R. Glasser and G.R. Newton. 1996. Comparative analysis of gap junction protein expression in porcine, equine and caprine endometrium. Biology of Reproduction. 54(Suppl 1): (abstr 472)

7. Burghardt, R.C., R. Barhoumi, M. Stickney, J.A. Bowen, B.M. Sanborn and M. Monga. 1995. Modulation of gap junctions in an immortalized human myometrial cell line. Biology of Reproduction. 52(Suppl 1):146.

8. Bowen, J.A., F.W. Bazer, G.R. Newton and R.C. Burghardt. 1995. Distribution of extracellular matrix and integrin subunits in uterine epithelium during the estrous cycle and early pregnancy in swine. Biology of Reproduction. 52(Suppl 1):154.

9. Burghardt, R.C., R. Barhoumi and J.A. Bowen. 1995. Rapid upregulation of intercellular communication by cyclic AMP in low and high passage immortalized rat granulosa cells. Society of Toxicology, 34th Annual Meeting.

10. Bowen, J.A., D.W. Weiss, G.R. Newton, F.W. Bazer and R.C. Burghardt. 1994. An in vitro model system for studying maternal recognition of pregnancy in pigs: A structural and functional study. Biology of Reproduction. 50(Suppl 1):62.

11. Hutchinson, R., C.B. Spainhour, R.H. Bailey, T.D. Phillips, J.A. Bowen, R. Barhoumi and R.C. Burghardt. 1994. Kinetic analysis of rhodamine 123 fluorescence reveals a triphasic pattern following treatment with several toxins. Society of Toxicology, 33rd Annual Meeting.

12. Barhoumi, R., J.A. Bowen, T.D. Phillips and R.C. Burghardt. 1993. Correlation between intracellular glutathione content and gap junctional intercellular communication. Society of Toxicology, 32nd Annual Meeting.

13. Bowen, J.A., D.W. Weiss, N.H. Ing and R.C. Burghardt. 1993. Structural and functional studies of polarized uterine epithelial cells cultured from small ruminants. Biology of Reproduction. 48(Suppl 1):117.

14. Barhoumi, R., J.A. Bowen, R.P. Lewis and R.C. Burghardt. 1992. Analysis of glutathione content and gap junctional intercellular communication. Gulf Coast Society of Toxicology.

15. Varner, D.D., J.A. Bowen and L. Johnson. 1992. Induction of capacitation and acrosome reaction of stallion spermatozoa by heparin. Assisted Reproductive Technology/Andrology Symposium, Munich, Germany.

16. Varner, D.D., J.A. Bowen and L. Johnson. 1992. Induction of capacitation and acrosome reaction of stallion spermatozoa by heparin. Assisted Reproductive Technology/Andrology Symposium, Costa Brava, Spain.

17. Bowen, J.A., D.W. Weiss, G.R. Newton and R.C. Burghardt. 1992. Structural and functional analysis of cultured caprine uterine epithelial cells. Molecular Biology of the Cell. 3(Suppl.):290a.

18. Johnson, L. and J.A. Bowen. 1991. The relationship of daily sperm production with sertoli cell number or testicular size begins with spermatogonia in horses. Biology of Reproduction. 44(Suppl 1):126.

19. Bowen, J.A., E.S. Fonda and E.A. Cogger. 1989. Effects of osmotically adjusted diluents on the freezing of boar spermatozoa. Journal of Animal Science. 68(Suppl 1):459-460.

20. Garcia, M.A., J.A. Bowen, E.S. Fonda and M.J. Burrill. 1989. Acrosin extraction and quantitation in porcine spermatozoa. Journal of Animal Science. 68(Suppl 1):183.

21. Bowen, J.A., E.S. Fonda and D.L. Kooyman. 1988. Ultrastructural study of goat spermatozoa frozen at different diluent osmolalities. Journal of Animal Science. 66(suppl 1).

22. Bowen, J.A., E.S. Fonda and D.L. Kooyman. 1988. A Morphological study of caprine spermatozoa frozen at different diluent osmolalities. Journal of Animal Science. 66(suppl 1).

 

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Art of Science: Image Analysis-Related Work

Published works:
1. Green Darner. 2005. Inside Front Cover. Bridgewater Review. 24(1) (with Kevin Curry)
2. Dragonfly Rose. 2005. Inside Back Cover. Bridgewater Review. 24(1) (with Kevin Curry)
3. Kaleidofly. Content Page Image. Discover Magazine. February, 2008

Website: www.kaleidofly.com 

International Competitions
Nikon Small World Competition: Thirty-Third Annual Competition – 17th Place
http://www.nikonsmallworld.com/gallery.php?grouping=year&year=2007&imagepos=17 

Windland Smith Rice International Awards with the Smithsonian Institute
Three of four submissions were selected as Finalists
Awarded “Highly Honored” for Kaleidofly Rose of a Painted Dragonfly.

Exhibitions
Nikon Small World Museum Tour
Rochester Institute of Technology, Rochester, NY, Jan. 2, 2008–Oct. 7, 2008
Marine Bio Lab, Woods Hole, MA, Jul. 25, 2008–Aug. 30, 2008
Fernbank Science Center, Atlanta, GA, May 10, 2008–July 08, 2008
American Museum of Science & Energy, Oak Ridge, TN, June 06, 2008–Aug. 10, 2008
Adventure Science Center, Nashville, TN, Aug. 29, 2008–Dec. 14, 2008
Texas Freshwater Fisheries Center, Athens, TX, Aug. 22, 2008–Oct. 26, 2008
New Mexico Museum of Natural History & Science, Albuquerque, NM, May 30, 2008–Aug. 17, 2008
Utah State University, Center for Integrated BioSystems, Logan, UT, May 16, 2008–Aug. 17, 2008
Tech Museum of Innovation, San Jose, CA, Aug. 29, 2008–Oct. 19, 2008
Science World, Vancouver, BC, Canada, Sept. 12, 2008–Nov. 2, 2008

Television Appearance
On May 21st, 2008, ABC News featured Small World in a segment hosted by Charles Gibson and reported by Ned Potter. The Kaleidofly was a featured image.
http://abcnews.go.com/video/playerIndex?id=4904018 

 

 

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Student Related Research Activity
Institutions of Mentored Students for Post-Baccalaureate Training
Masters
New York University (M.S.)
University of Manchester (M.S. Program)
University of Massachusetts, Boston (M.S. Biotechnology)
University of Massachusetts, Dartmouth (M.S. Nursing)
University of Massachusetts, Worcester (M.S. Nurse Practitioner)

Professional
Kansas City University of Medicine and Biosciences (D.O)
Meharry Medical College (M.D. Program)
Tufts Vet School (3 accepted into the D.V.M. program, one declined)
Ross University (D.V.M. Program; also one of only 25 foreign students accepted at the Royal Veterinary College, London)
Purdue University (D.V.M. Program)
University of Minnesota (D.V.M. Program)
Oklahoma State University (Joint D.V.M/Ph.D. Program)

Doctor of Philosophy
California Institute of Technology -- Ph.D. Program
UNC Chapel Hill – 2 students in Ph.D. Programs
Cornell University – Ph.D. Program
University of Connecticutt – Ph.D. Program
Northwestern University – Ph.D. Program
University of Pittsburg – Ph.D. Program
University of Buffalo – Ph.D. Program

Student Presentations
8th Annual Bridgewater State College Undergraduate Research, Spring 2008
Student: Brian Agbor-Etang*
Title: Effect of Caspase-3-Inhibitor on Ethanol Induced Apoptosis in Rat Liver Epithelial Cells
Student: Ryan Bagley*
Title: Effects of Alcohol Induced Apoptosis on Rat Liver Epithelial Cells: Don’t Drink and Divide
Student: Allison Galanis*
Title: Techniques in Clone 9 Rat Hepatic Epithelium Cell Cultures
Student: Janelle Mapes*
Title: Effect of Reactive Oxygen Species on the Onset of Apoptosis
Student: Betsy Witt Powers*
Title: Integrin and Focal Adhesion Kinase Expression in Anchorage-Independent Spontaneously Immortalized Granulosa Cell Cultures

7th Annual Bridgewater State College Undergraduate Research, Spring 2007
Student: Betsy Witt-Powers*
Title: Cell-Cycle-Dependent Susceptibility to Apoptosis in Synchronized Rat Liver Epithelium Cell Cultures
Student: Chelsea Lawrence*
Title: The Role of the BCL-2 Family in Cellular Stress in Rat Liver Epithelial Cells
Student: Vanessa Fernandes*
Title: An Investigation Of The Expression Of Heat Shock Proteins & Their Effect On Apoptosis In Clone 9 Cells
Student: Alden Gustafson*
Title: Growth And Fluorescent Image Analyses Of A Spontaneously Immortalized Granulosa Cell Line From The Rat Ovarian Follicle, And Their Correlation To Apoptosis (Cell Suicide)"

National Council for Undergraduate Research, Poster Presentation, Dominican University of California, San Rafael, CA. April 2007
Student: Vanessa Fernandes*
Abstract: An investigation of the expression of αB-crystallin and its effect on apoptosis in liver epithelial cells.
Student: Megan Dobro
Abstract: The effect of the SMSIARL peptide tag and sucrose purification on P14-Liposome binding in prostate tissue.

6th Annual Bridgewater State College Undergraduate Research, Spring 2006
Student: Megan Dobro*
Title: Investigating the Cell Cycle and Apoptotic Pathways
Student: Vanessa Fernandes*
Title: Assays in Apoptosis and its Relationship to Cancer Biology
Student: Alden Gustafson*
Title: Laboratory Techniques Used to Study Apoptosis and the Cell Cycle

American Chemical Society National Meeting, San Diego, CA, March 13-17, 2005
Karen DeBalsi, Jeff Bowen and Ed Brush,
Synthesis, purification, characterization, and biological evaluation of dialkylester glutathione conjugates with 3-methyleneoxindole as potential therapeutic agents

National Council for Undergraduate Research, Poster Presentation Student: Karyn O’Connell*: April 2005
Abstract: Transfection Efficiency of Liposomes in Liver Epithelial Cells

5th Annual Bridgewater State College Undergraduate Research, Spring 2005
Student: Vanessa Fernandes*
Title: To Die or Not to Die, That is the Question!
Student: Laura Grindell*
Title: The Effect of Etoposide on Clone 9 Cells
Student: Karyn O'Connell*
Title: Proteins that Beat the Heat: The Expression of GFP,
aB-crystallin, and Hsp27 in Clone-9 Liver Epithelial Cells.
Student: Michele Parenteau*
Title: Investigating the Role of Mebendazole in Apoptotic Cell Death

4th Annual Bridgewater State College Undergraduate Research, Spring 2004
Student: Melissa Amistadi*
Title: The Effect of Diosgenin on C2C12 Cells
Student: Rosemary Barrett*
Title: Relationship Between Release of Smac/DIABLO and Cytochrome-c in Cisplatin-Induced Apoptosis of Myoblast Cells
Student: Karen L. DeBalsi*
Title: Synthesis, Purification, and Characterization of Dialkylester Glutathione Conjugates with 3-Methyleneoxindole as Potential Therapeutic Agents
Student: Monica M. Laronda*
Title: Investigation of a potential anti-cancer agent: 3-methyleneoxindole
Student: Karyn O'Connell*
Title: Death by Etoposide
Student: Jaime Rochefort*
Title: p53: A Life or Death Situation

American Chemical Society National Meeting: San Diego, CA, April 1-5, 2001
Stephen J. Godin, Edward J. Brush, and Jeffery Bowen
Synthesis Of Glutathione Diester Conjugates With 3-Methyleneoxindole As Potential Prodrug Inhibitors Of Anti-Cancer Target Enzymes”

Annual Undergraduate Poster Session on Capitol Hill: Washington, D.C., March 29, 2001.
Stephen Godin, Edward J. Brush, and Jeffery Bowen
Synthesis And Evaluation Of Glutathione-3-Methyleneoxindole Diethylester: A Potential Prodrug Inhibitor Of The Anticancer Target Enzyme Glyoxalase I

American Chemical Society Northeast Regional Meeting: University of Connecticut, June 2000.
Stephen J. Godin, Louis Crowley, Jeffery Bowen, and Edward J. Brush
The Synthesis of Diethylester Glutathione Conjugates as potential Cell Membrane Permeable “Arrows” Against Anti-Cancer Target Enzymes

Student Grants
Adrian Tinsley Program for Undergraduate Research (ATP):
Semester Grants: Awarded $250 for research supplies
February 2008
Student: Brian Agbor-Etang*
Title: Investigating the Effects of Inhibiting Alcohol-Induced Apoptosis in Rat Hepatocytes
Student: Ryan Bagley*
Title: Investigations into Mitochondrial Apoptosis Pathway
Student: Allison Galanis*
Title: Techniques in Clone 9 Rat Hepatic Epithelium Cell Cultures
Student: Janelle Mapes*
Title: The Effect of Reactive Oxygen Species on the Onset of Apoptosis
Student: Betsy Witt Powers*
Title: Focal Adhesion Kinase Expression in Anchorage-Independent Spontaneously Immortalized Granulosa Cell Cultures

September 2007
Student: Betsy Witt-Powers*
Title: Cell-Cycle-Dependent Susceptibility to Apoptosis in Synchronized Rat Liver Epithelium Cell Cultures

February 2007
Student: Chelsea Lawrence* Title: The Role of the BCL-2 Family in Cellular Stress in Rat Liver Epithelial Cells
Student: Betsy Witt-Powers* Title: Cell-Cycle-Dependent Susceptibility to Apoptosis in Synchronized Rat Liver Epithelium Cell Cultures

September 2006
Student: Vanessa Fernandes* Title: An Investigation Of The Expression Of Heat Shock Proteins & Their Effect On Apoptosis In Clone 9 Cells

Student: Alden Gustafson* Growth And Fluorescent Image Analyses Of A Spontaneously Immortalized Granulosa Cell Line From The Rat Ovarian Follicle, And Their Correlation To Apoptosis (Cell Suicide)"
February 2006:
Student: Megan Dobro* Title: Investigating the Cell Cycle and Apoptotic Pathways
Student: Vanessa Fernandes* Title: Assays in Apoptosis and its Relationship to Cancer Biology
Student: Alden Gustafson* Title: Introduction to Laboratory Techniques to Aid in the Study of Apoptosis and the Cell Cycle in Rat Liver Epithelium Cell Cultures

September 2005
Student: Megan Dobro* Title: Investigating the Cell Cycle of a Rodent Hepatic Cell Line

February 2005
Student: Vanessa Fernandes* Title: To Die or Not to Die, That is the Question!
Student: Laura Grindell* Title: The Effect of Etoposide on Clone 9 Cells
Student: Michele Parenteau Title: Investigating the Role of Mebendazole in Apoptotic Cell Death

September 2004
Student: Karyn O'Connell* Title: Proteins that Beat the Heat: The Expression of GFP, αB-crystallin, and Hsp27 in Clone-9 Liver Epithelial Cells.

February 2004
Student: Melissa Amistadi* Title: The Effect of Diosgenin on C2C12 Cells
Student: Rosemary Barrett* Title: Relationship Between Release of Smac/DIABLO and Cytochrome-c in Cisplatin-Induced Apoptosis of Myoblast Cells
Student: Jaime Rochefort* Title: p53: A Life or Death Situation
Student: Karyn O’Connell* Title: Death by Etoposide

Shea Scholar
Student: Stephen J. Godin,
Project: “The Synthesis and Evaluation of the Diethylester Conjugate of Glutathione and 3-Methyleneoxindole”, September 2000, Mentors: Dr. Edward Brush, Department of Chemical Sciences and Dr. Jeffery Bowen, Department of Biological Sciences.
* Denotes co-mentoring with Dr. Merideth Krevosky.

National and Regional Presentations Centered on Undergraduate Research:

1. Edward J. Brush, Steve Godin, and Jeff Bowen. Synthesis Of Dialkylester GSH Conjugates With 3-Methyleneoxindole: Potential Cell Membrane Permeable Prodrug Inhibitors Of GSH-Dependent Anti-Cancer Target Enzymes. ACS National Meeting, San Diego, April 2001.

2. Edward J. Brush, Jeff Bowen, and Steve Godin. Synthesis Of The Diethylester Glutathione Conjugate With 3-Methyleneoxindole: A Potential Prodrug Inhibitor Of Glutathione-Dependent Enzymes. CART Celebration V, May 2001.

3. Edward J. Brush, Steve Godin, and Jeff Bowen. Synthesis Of The Diethylester Glutathione Conjugate With 3-Methyleneoxindole: A Potential Prodrug Inhibitor Of Glutathione-Dependent Enzymes. Gordon Research Conference on Bioorganic Chemistry, June 2001.

4. Edward J. Brush, Steve Godin, and Jeff Bowen. Synthesis Of The Diethylester Glutathione Conjugate With 3-Methyleneoxindole: A Potential Prodrug Inhibitor Of Glutathione-Dependent Enzymes. American Chemical Society Northeastern Regional Meeting, University of New Hampshire, June 24-27, 2001.


 

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