Introduction to Protein Structure
Overall Charge on a Peptide -- Example 1
The only ionizable groups in this peptides are the amino group (pka ~ 9) and the carboxyl group (pKa ~ 3) at each end of the molecule.
Thus, the net charge on this peptide at three different pH's ( 2, 7 and 11) is as follows:
|Charge on Functional Group|
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