Frank R. Gorga, Ph.D.
  Biochemistry I (CHEM 461)
 
   

Announcements:

Welcome!
     

Problem Set #4 due Thursday, 19 Nov.

 

     
Course Documents
Syllabus, Lecture
Statement on Plagiarism
   
. Due Dates for Assignments, Lab Reports, etc. (from the syllabus)
 
. Student's Companion Site for Voet, Voet & Pratt
 
   
. Lab Stuff
Syllabus, Lab
Lab Schedule
    Lab Handouts, etc.  
       
  Misc. Stuff  
    pKa values for some common buffers (for Problem Set #1)  
 

 

Lecture Notes
(Slides used in class; these are added as the semester progresses)
 

These files are Adobe pdf versions of the Power Point files I use in class. You will need Adobe Acrobat Reader to open these files for viewing or printing.

Most of the figures used here come directly from the textbook and are Copyright 1999 or 2008 by Wiley & Sons. Other figures are my own and are copyright 2000-2004 by F.R. Gorga.

Chapter 01 -- Introduction

Chapter 02 - Water, Bonding, etc.
Chapter 03 - Nucleotides & Nucleic Acids

"Quick and Dirty" DNA Structure (as used in class; requires CHIME)

03a - DNA Tools

PCR Rap

Chapter 04 - Amino Acids

Chapter 05 - Proteins, Part 1

Protein Sequence Determination (guided exploration)

Protein Tools:

SDS-PAGE

Affinity Chromatography

Gel Filtration (AKA Size Exclusion Chromatography or SEC)

Hydrophobic Interaction Chromatography (HIC)

Ion Exchange Chromatography

 

Chapter 06 - Proteins, Part 2

"Quick & Dirty Protein Structure" (as used in class; requires CHIME)

Protein Structure (complete version)

Protein Folding Animations (via YouTube):

Version 1 / Version 2

Protein Dynamics Animations (via YouTube)

Version 1 / Version 2 / Version 3 / Version 4

 

Chapter 07 - Myoglobin & Hemoglobin

07a -- Sickle Cell Disease
07b -- Antibodies

Chapter 08 - Carbohydrates

Chapter 09 - Lipids & Membranes

Chapter 10 -

Chapter 11 Enzymatic Catalysis

11a - Lysozyme

Lysozyme in 3-D (chime required)

Kinemage from text / Interactive Exercise from text

11b - Serine Proteases

Kinemage from text

Chapter 12 - Enzyme Kinetics

Handout on Inhibition / Determination of Ki

Chapte 24 - Nucleic Acid Structure / DNA Binding Proteins

Chapter 24 - DNA Replication

Watson & Crick 1953 Nature paper

Chapter 25 - Transcription
Chapter 26a - Protein Synthesis, Part 1

Chapter 26b - Protein Synthesis, Part 2

The Protein Synthesis Dance (a real classic of the 60's!)

Chapter 27 -- Control of Gene Expression (1,455 KB)
 
 
 

 


Page maintained by F.R. Gorga  
Last updated: 03-Sep-2009